Selective Preservation of Bone Marrow Mature Recirculating but Not Marginal Zone B Cells in Murine Models of Chronic Inflammation

Inflammation promotes granulopoiesis over B lymphopoiesis in the bone marrow (BM). We studied B cell homeostasis in two murine models of T cell mediated chronic inflammation, namely calreticulin-deficient fetal liver chimeras (FLC), which develop severe blepharitis and alopecia due to T cell hyper r...

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Autori principali: Traggiai, Elisabetta, Casati, Anna, Frascoli, Michela, Porcellini, Simona, Ponzoni, Maurilio, Sanvito, Francesca, Leng, Lin, Bucala, Richard, Moretta, Lorenzo, Grassi, Fabio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889832/
https://ncbi.nlm.nih.gov/pubmed/20582316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011262
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