PYY(3–36) and Oxyntomodulin Can Be Additive in Their Effect on Food Intake in Overweight and Obese Humans

OBJECTIVE: Peptide YY(3–36) (PYY(3–36)), a Y2 receptor agonist, and oxyntomodulin, a glucagon-like peptide 1 (GLP-1) receptor agonist, are cosecreted by intestinal L-cells after each meal. Separately each hormone acts as an endogenous satiety signal and reduces appetite in humans when infused intrav...

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Hlavní autoři: Field, Benjamin C.T., Wren, Alison M., Peters, Veronique, Baynes, Kevin C.R., Martin, Niamh M., Patterson, Michael, Alsaraf, Sara, Amber, Vian, Wynne, Katie, Ghatei, Mohammad A., Bloom, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2010
Témata:
Obesity Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889762/
https://ncbi.nlm.nih.gov/pubmed/20357366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1859
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