Early Hepatic Insulin Resistance Precedes the Onset of Diabetes in Obese C57BLKS-db/db Mice

OBJECTIVE: To identify metabolic derangements contributing to diabetes susceptibility in the leptin receptor–deficient obese C57BLKS/J-db/db (BKS-db) mouse strain. RESEARCH DESIGN AND METHODS: Young BKS-db mice were used to identify metabolic pathways contributing to the development of diabetes. Usi...

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Hlavní autoři: Davis, Richard C., Castellani, Lawrence W., Hosseini, Maryam, Ben-Zeev, Osnat, Mao, Hui Z., Weinstein, Michael M., Jung, Dae Young, Jun, John Y., Kim, Jason K., Lusis, Aldons J., Péterfy, Miklós
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889760/
https://ncbi.nlm.nih.gov/pubmed/20393148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0878
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