Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization.

The principal neutralization determinant (PND) of human immunodeficiency virus type 1 envelope glycoprotein gp120 contains a conserved GPG sequence. The effects of a 29-amino-acid deletion of most of the PND, a 3-amino-acid deletion in the GPG sequence, and 16 single-amino-acid substitutions in the...

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Vydáno v:	J Virol
Hlavní autoři:	Grimaila, R J, Fuller, B A, Rennert, P D, Nelson, M B, Hammarskjöld, M L, Potts, B, Murray, M, Putney, S D, Gray, G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1875-1883.1992
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