Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization.

The principal neutralization determinant (PND) of human immunodeficiency virus type 1 envelope glycoprotein gp120 contains a conserved GPG sequence. The effects of a 29-amino-acid deletion of most of the PND, a 3-amino-acid deletion in the GPG sequence, and 16 single-amino-acid substitutions in the...

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Bibliografski detalji
Glavni autori: Grimaila, R J, Fuller, B A, Rennert, P D, Nelson, M B, Hammarskjöld, M L, Potts, B, Murray, M, Putney, S D, Gray, G
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC288974/
https://ncbi.nlm.nih.gov/pubmed/1548744
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