Učitavanje...

Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus

OBJECTIVE: HMG-CoA reductase inhibitors have been shown to upregulate GTP cyclohydrolase I (GTPCH-I), the key enzyme for tetrahydrobiopterin de novo synthesis and to normalize tetrahydrobiopterin levels in hyperglycemic endothelial cells. We sought to determine whether in vivo treatment with the HMG...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Wenzel, Philip, Daiber, Andreas, Oelze, Matthias, Brandt, Moritz, Closs, Ellen, Xu, Jian, Thum, Thomas, Bauersachs, Johann, Ertl, Georg, Zou, Ming-Hui, Förstermann, Ulrich, Müunzel, Thomas
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889614/
https://ncbi.nlm.nih.gov/pubmed/18061195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.10.003
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!