Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development

Cerebellar neurons are generated from two germinal neuroepithelia: the ventricular zone (VZ) and rhombic lip. Signaling mechanisms that maintain the proliferative capacity of VZ resident progenitors remain elusive. We reveal that Sonic hedgehog (Shh) signaling is active in the cerebellar VZ and esse...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Xi, Liu, Jiang, Ketova, Tatiana, Fleming, Jonathan T., Grover, Vandana K., Cooper, Michael K., Litingtung, Ying, Chiang, Chin
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889567/
https://ncbi.nlm.nih.gov/pubmed/20400693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911838107
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