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Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development

Cerebellar neurons are generated from two germinal neuroepithelia: the ventricular zone (VZ) and rhombic lip. Signaling mechanisms that maintain the proliferative capacity of VZ resident progenitors remain elusive. We reveal that Sonic hedgehog (Shh) signaling is active in the cerebellar VZ and esse...

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Main Authors: Huang, Xi, Liu, Jiang, Ketova, Tatiana, Fleming, Jonathan T., Grover, Vandana K., Cooper, Michael K., Litingtung, Ying, Chiang, Chin
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889567/
https://ncbi.nlm.nih.gov/pubmed/20400693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911838107
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