Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development

Cerebellar neurons are generated from two germinal neuroepithelia: the ventricular zone (VZ) and rhombic lip. Signaling mechanisms that maintain the proliferative capacity of VZ resident progenitors remain elusive. We reveal that Sonic hedgehog (Shh) signaling is active in the cerebellar VZ and esse...

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Detalhes bibliográficos
Main Authors: Huang, Xi, Liu, Jiang, Ketova, Tatiana, Fleming, Jonathan T., Grover, Vandana K., Cooper, Michael K., Litingtung, Ying, Chiang, Chin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889567/
https://ncbi.nlm.nih.gov/pubmed/20400693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911838107
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