MHC class I D(k) expression in hematopoietic and nonhematopoietic cells confers natural killer cell resistance to murine cytomegalovirus

NK cell-mediated murine cytomegalovirus (MCMV) resistance (Cmv(r)) is under H-2(k) control in MA/My mice, but the underlying gene(s) is unclear. Prior genetic analysis mapped Cmv(r) to the MHC class I (MHC-I) D(k) gene interval. Because NK cell receptors are licensed by and responsive to MHC class I...

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Detalhes bibliográficos
Main Authors: Xie, Xuefang, Stadnisky, Michael D., Coats, Ebony R., Ahmed Rahim, Mir Munir, Lundgren, Alyssa, Xu, Wenhao, Makrigiannis, Andrew P., Brown, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889336/
https://ncbi.nlm.nih.gov/pubmed/20421478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913126107
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