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Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells

Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The β-chemokine CCL17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases. Using an atopic dermatitis model, we show that CCL17-de...

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Detalhes bibliográficos
Main Authors: Stutte, Susanne, Quast, Thomas, Gerbitzki, Nancy, Savinko, Terhi, Novak, Nina, Reifenberger, Julia, Homey, Bernhard, Kolanus, Waldemar, Alenius, Harri, Förster, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889308/
https://ncbi.nlm.nih.gov/pubmed/20421491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906126107
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