B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus–associated acute liver failure

Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells leading to multiorgan failure. The mechanisms whereby HBV induces ALF are unknown. Here, we show that liver tissue collected at the time of liver transplantation in two...

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Hlavní autoři: Farci, Patrizia, Diaz, Giacomo, Chen, Zhaochun, Govindarajan, Sugantha, Tice, Ashley, Agulto, Liane, Pittaluga, Stefania, Boon, Denali, Yu, Claro, Engle, Ronald E., Haas, Mark, Simon, Richard, Purcell, Robert H., Zamboni, Fausto
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889296/
https://ncbi.nlm.nih.gov/pubmed/20421498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003854107
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