Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues

Methylation of cytosine residues within the CpG dinucleotide in mammalian cells is an important mediator of gene expression, genome stability, X-chromosome inactivation, genomic imprinting, chromatin structure, and embryonic development. The majority of CpG sites in mammalian cells is methylated in...

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Hlavní autoři: Velasco, Guillaume, Hubé, Florent, Rollin, Jérôme, Neuillet, Damien, Philippe, Cathy, Bouzinba-Segard, Haniaa, Galvani, Angélique, Viegas-Péquignot, Evani, Francastel, Claire
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889045/
https://ncbi.nlm.nih.gov/pubmed/20439742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000473107
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