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Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases

The correct establishment and maintenance of DNA methylation patterns are critical for mammalian development and the control of normal cell growth and differentiation. DNA methylation has profound effects on the mammalian genome, including transcriptional repression, modulation of chromatin structur...

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Hlavní autoři: Walton, Emma L., Francastel, Claire, Velasco, Guillaume
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192629/
https://ncbi.nlm.nih.gov/pubmed/25198254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology3030578
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