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Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases

The correct establishment and maintenance of DNA methylation patterns are critical for mammalian development and the control of normal cell growth and differentiation. DNA methylation has profound effects on the mammalian genome, including transcriptional repression, modulation of chromatin structur...

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Detalhes bibliográficos
Main Authors: Walton, Emma L., Francastel, Claire, Velasco, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192629/
https://ncbi.nlm.nih.gov/pubmed/25198254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology3030578
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