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Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy

The folding of proteins in living cells may start during their synthesis when the polypeptides emerge gradually at the ribosomal exit tunnel. However, our current understanding of cotranslational folding processes at the atomic level is limited. We employed NMR spectroscopy to monitor the conformati...

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Библиографические подробности
Главные авторы: Eichmann, Cédric, Preissler, Steffen, Riek, Roland, Deuerling, Elke
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889043/
https://ncbi.nlm.nih.gov/pubmed/20439768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914300107
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