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Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy

The folding of proteins in living cells may start during their synthesis when the polypeptides emerge gradually at the ribosomal exit tunnel. However, our current understanding of cotranslational folding processes at the atomic level is limited. We employed NMR spectroscopy to monitor the conformati...

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Bibliografiske detaljer
Main Authors: Eichmann, Cédric, Preissler, Steffen, Riek, Roland, Deuerling, Elke
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889043/
https://ncbi.nlm.nih.gov/pubmed/20439768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914300107
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