Genome-wide and fine-resolution association analysis of malaria in West Africa

We report a genome-wide association (GWA) study of severe malaria in The Gambia. The initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a replication study included 3,400 children. We used this to examine the performance of GWA methods in Africa. We found conside...

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Detalhes bibliográficos
Main Authors: Jallow, Muminatou, Teo, Yik Ying, Small, Kerrin S, Rockett, Kirk A, Deloukas, Panos, Clark, Taane G, Kivinen, Katja, Bojang, Kalifa A, Conway, David J, Pinder, Margaret, Sirugo, Giorgio, Sisay-Joof, Fatou, Usen, Stanley, Auburn, Sarah, Bumpstead, Suzannah J, Campino, Susana, Coffey, Alison, Dunham, Andrew, Fry, Andrew E, Green, Angela, Gwilliam, Rhian, Hunt, Sarah E, Inouye, Michael, Jeffreys, Anna E, Mendy, Alieu, Palotie, Aarno, Potter, Simon, Ragoussis, Jiannis, Rogers, Jane, Rowlands, Kate, Somaskantharajah, Elilan, Whittaker, Pamela, Widden, Claire, Donnelly, Peter, Howie, Bryan, Marchini, Jonathan, Morris, Andrew, SanJoaquin, Miguel, Achidi, Eric Akum, Agbenyega, Tsiri, Allen, Angela, Amodu, Olukemi, Corran, Patrick, Djimde, Abdoulaye, Dolo, Amagana, Doumbo, Ogobara K, Drakeley, Chris, Dunstan, Sarah, Evans, Jennifer, Farrar, Jeremy, Fernando, Deepika, Hien, Tran Tinh, Horstmann, Rolf D, Ibrahim, Muntaser, Karunaweera, Nadira, Kokwaro, Gilbert, Koram, Kwadwo A, Lemnge, Martha, Makani, Julie, Marsh, Kevin, Michon, Pascal, Modiano, David, Molyneux, Malcolm E, Mueller, Ivo, Parker, Michael, Peshu, Norbert, Plowe, Christopher V, Puijalon, Odile, Reeder, John, Reyburn, Hugh, Riley, Eleanor M, Sakuntabhai, Anavaj, Singhasivanon, Pratap, Sirima, Sodiomon, Tall, Adama, Taylor, Terrie E, Thera, Mahamadou, Troye-Blomberg, Marita, Williams, Thomas N, Wilson, Michael, Kwiatkowski, Dominic P
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889040/
https://ncbi.nlm.nih.gov/pubmed/19465909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.388
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