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Development of flexible-heteroarotinoids for kidney cancer

Potential chemopreventive and therapeutic value of the lead Flexible Heteroarotinoid (Flex-Het), SHetA2, was indicated by growth inhibition of multiple cancer cell lines. The objective of this study was to evaluate the SHetA2 mechanism and in vivo activity in kidney cancer. SHetA2 induced apoptosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Tongzu, Masamha, Chioniso Patience, Chengedza, Shylet, Berlin, K. Darrell, Lightfoot, Stan, He, Feng, Benbrook, Doris Mangiaracina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888972/
https://ncbi.nlm.nih.gov/pubmed/19417155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1069
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