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Aerosol Gemcitabine: Preclinical Safety and In Vivo Antitumor Activity in Osteosarcoma-Bearing Dogs

BACKGROUND: Osteosarcoma is the most common skeletal malignancy in the dog and in young humans. Although chemotherapy improves survival time, death continues to be attributed to metastases. Aerosol delivery can provide a strategy with which to improve the lung drug delivery while reducing systemic t...

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Autori principali: Rodriguez, Carlos O., Crabbs, Torrie A., Wilson, Dennis W., Cannan, Virginia A., Skorupski, Katherine A., Gordon, Nancy, Koshkina, Nadya, Kleinerman, Eugenie, Anderson, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888930/
https://ncbi.nlm.nih.gov/pubmed/19803732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2009.0773
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