The antitumor activity of the fungicide ciclopirox

Ciclopirox olamine (CPX) is a synthetic antifungal agent clinically used to treat mycoses of the skin and nails. Here we show that CPX inhibited tumor growth in human breast cancer MDA-MB-231 xenografts. To unveil the underlying mechanism, we further studied the antitumor activity of CPX in cell cul...

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Detalhes bibliográficos
Main Authors: Zhou, Hongyu, Shen, Tao, Luo, Yan, Liu, Lei, Chen, Wenxing, Xu, Baoshan, Han, Xiuzhen, Pang, Jia, Rivera, Chantal A., Huang, Shile
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888914/
https://ncbi.nlm.nih.gov/pubmed/20225320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25255
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