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Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy

Dietary energy restriction has been shown to repress both mammary tumorigenesis and aggressive mammary tumor growth in animal studies. Metformin, a caloric restriction mimetic, has a long history of safe use as an insulin sensitizer in diabetics and has been shown to reduce cancer incidence and canc...

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Detalhes bibliográficos
Main Authors: Phoenix, Kathryn N., Vumbaca, Frank, Fox, Melissa M., Evans, Rebecca, Claffey, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888909/
https://ncbi.nlm.nih.gov/pubmed/20204498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0647-z
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