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Model-Based Quality Assessment and Base-Calling for Second-Generation Sequencing Data

Second-generation sequencing (sec-gen) technology can sequence millions of short fragments of DNA in parallel, and is capable of assembling complex genomes for a small fraction of the price and time of previous technologies. In fact, a recently formed international consortium, the 1,000 Genomes Proj...

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Detalhes bibliográficos
Main Authors: Bravo, Héctor Corrada, Irizarry, Rafael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888717/
https://ncbi.nlm.nih.gov/pubmed/19912177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2009.01353.x
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