Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

Adeno-associated virus (AAV)-mediated microdystrophin gene therapy holds great promise for treating Duchenne muscular dystrophy (DMD). Previous studies have revealed excellent skeletal muscle protection. Cardiac muscle is also compromised in DMD patients. Here we show that a single intravenous injec...

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Main Authors: Bostick, Brian, Yue, Yongping, Lai, Yi, Long, Chun, Li, Dejia, Duan, Dongsheng
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2008
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888653/
https://ncbi.nlm.nih.gov/pubmed/18666839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.058
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