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Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

Adeno-associated virus (AAV)-mediated microdystrophin gene therapy holds great promise for treating Duchenne muscular dystrophy (DMD). Previous studies have revealed excellent skeletal muscle protection. Cardiac muscle is also compromised in DMD patients. Here we show that a single intravenous injec...

詳細記述

保存先:
書誌詳細
主要な著者: Bostick, Brian, Yue, Yongping, Lai, Yi, Long, Chun, Li, Dejia, Duan, Dongsheng
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888653/
https://ncbi.nlm.nih.gov/pubmed/18666839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.058
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