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Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

Adeno-associated virus (AAV)-mediated microdystrophin gene therapy holds great promise for treating Duchenne muscular dystrophy (DMD). Previous studies have revealed excellent skeletal muscle protection. Cardiac muscle is also compromised in DMD patients. Here we show that a single intravenous injec...

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Autori principali: Bostick, Brian, Yue, Yongping, Lai, Yi, Long, Chun, Li, Dejia, Duan, Dongsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888653/
https://ncbi.nlm.nih.gov/pubmed/18666839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.058
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