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Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

Adeno-associated virus (AAV)-mediated microdystrophin gene therapy holds great promise for treating Duchenne muscular dystrophy (DMD). Previous studies have revealed excellent skeletal muscle protection. Cardiac muscle is also compromised in DMD patients. Here we show that a single intravenous injec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bostick, Brian, Yue, Yongping, Lai, Yi, Long, Chun, Li, Dejia, Duan, Dongsheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888653/
https://ncbi.nlm.nih.gov/pubmed/18666839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.058
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