Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

Adeno-associated virus (AAV)-mediated microdystrophin gene therapy holds great promise for treating Duchenne muscular dystrophy (DMD). Previous studies have revealed excellent skeletal muscle protection. Cardiac muscle is also compromised in DMD patients. Here we show that a single intravenous injec...

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Detalles Bibliográficos
Autores principales: Bostick, Brian, Yue, Yongping, Lai, Yi, Long, Chun, Li, Dejia, Duan, Dongsheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2008
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888653/
https://ncbi.nlm.nih.gov/pubmed/18666839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.058
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