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AMPKα1 Deletion Shortens Erythrocyte Life Span in Mice: ROLE OF OXIDATIVE STRESS

AMP-activated protein kinase (AMPK) is an energy sensor essential for maintaining cellular energy homeostasis. Here, we report that AMPKα1 is the predominant isoform of AMPK in murine erythrocytes and mice globally deficient in AMPKα1 (AMPKα1(−/−)), but not in those lacking AMPKα2, and the mice had...

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Hlavní autoři: Wang, Shaobin, Dale, George L., Song, Ping, Viollet, Benoit, Zou, Ming-hui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888409/
https://ncbi.nlm.nih.gov/pubmed/20392689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102467
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