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Choline Promotes Nicotinic Receptor α4 + β2 Up-regulation

Neuronal nicotinic acetylcholine receptors (nAChR) composed of α4 + β2 subunits, the high affinity nicotine-binding site in the mammalian brain, up-regulate in response to chronic nicotine exposure. The identities of endogenous mediators of this process are unknown. We find that choline also up-regu...

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書目詳細資料
Main Authors: Gahring, Lorise C., Vasquez-Opazo, Gustavo A., Rogers, Scott W.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888390/
https://ncbi.nlm.nih.gov/pubmed/20392695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108803
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