Nitric Oxide Binds to the Proximal Heme Coordination Site of the Ferrocytochrome c/Cardiolipin Complex: FORMATION MECHANISM AND DYNAMICS

Mammalian mitochondrial cytochrome c interacts with cardiolipin to form a complex (cyt. c/CL) important in apoptosis. Here we show that this interaction leads to structural changes in ferrocytochrome c that leads to an open coordinate site on the central iron, resulting from the dissociation of the...

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Bibliografiske detaljer
Main Authors: Silkstone, Gary, Kapetanaki, Sofia M., Husu, Ivan, Vos, Marten H., Wilson, Michael T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888389/
https://ncbi.nlm.nih.gov/pubmed/20395293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067736
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