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High Affinity S-Adenosylmethionine Plasma Membrane Transporter of Leishmania Is a Member of the Folate Biopterin Transporter (FBT) Family

S-Adenosylmethionine (AdoMet) is an important methyl group donor that plays a central role in many essential biochemical processes. The parasite Leishmania can both synthesize and transport AdoMet. Leishmania cells resistant to the antifolate methotrexate due to a rearrangement in folate biopterin t...

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Bibliographische Detailangaben
Hauptverfasser: Dridi, Larbi, Ahmed Ouameur, Amin, Ouellette, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888387/
https://ncbi.nlm.nih.gov/pubmed/20406813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114520
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