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Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes

INTRODUCTION: The objective of this study was to model the effects of transforming growth factor beta (TGF-β) and platelet-derived growth factor (PDGF), both present in rheumatoid arthritis (RA) synovia, on the behavior of fibroblast-like synoviocytes (FLS) in response to pro-inflammatory cytokine (...

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Detalhes bibliográficos
Main Authors: Rosengren, Sanna, Corr, Maripat, Boyle, David L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888219/
https://ncbi.nlm.nih.gov/pubmed/20380722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2981
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