Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes

The mechanisms by which cyclophilin A (CypA) governs hepatitis C virus (HCV) replication remain unknown. Since CypA binds two essential components of the HCV replication complex (RC) – the polymerase NS5B and the phosphoprotein NS5A – we asked in this study whether CypA regulates their RC associatio...

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Autors principals: Chatterji, Udayan, Bobardt, Michael D., Lim, Precious, Gallay, Philippe A.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2010
Matèries:
Animal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888154/
https://ncbi.nlm.nih.gov/pubmed/20107018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.018531-0
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