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Vitamin A and Retinoic Acid Act Synergistically to Increase Lung Retinyl Esters During Normoxia and Reduce Hyperoxic Lung Injury in Newborn Mice

We have shown that vitamin A (VA) and retinoic acid (RA) synergistically increase lung retinyl ester content in neonatal rats. To confirm if this biochemical synergism attenuates early neonatal hyperoxic lung injury in mice, we exposed newborn C57BL/6 mice to 95% O(2) or air from birth to 4 days. Th...

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Detalhes bibliográficos
Main Authors: James, Masheika L., Ross, A. Catharine, Bulger, Arlene, Philips, Joseph B., Ambalavanan, Namasivayam
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888037/
https://ncbi.nlm.nih.gov/pubmed/20220550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181dbac3d
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