Protective Unfolded Protein Response in Human Pancreatic Beta Cells Transplanted into Mice

BACKGROUND: There is great interest about the possible contribution of ER stress to the apoptosis of pancreatic beta cells in the diabetic state and with islet transplantation. METHODS AND FINDINGS: Expression of genes involved in ER stress were examined in beta cell enriched tissue obtained with la...

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Detalhes bibliográficos
Main Authors: Kennedy, Jeffrey, Katsuta, Hitoshi, Jung, Min-Ho, Marselli, Lorella, Goldfine, Allison B., Balis, Ulysses J., Sgroi, Dennis, Bonner-Weir, Susan, Weir, Gordon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887848/
https://ncbi.nlm.nih.gov/pubmed/20585452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011211
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