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Live Recombinant Salmonella Typhi Vaccines Constructed to Investigate the Role of rpoS in Eliciting Immunity to a Heterologous Antigen

We hypothesized that the immunogenicity of live Salmonella enterica serovar Typhi vaccines expressing heterologous antigens depends, at least in part, on its rpoS status. As part of our project to develop a recombinant attenuated S. Typhi vaccine (RASTyV) to prevent pneumococcal diseases in infants...

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Main Authors: Shi, Huoying, Santander, Javier, Brenneman, Karen E., Wanda, Soo-Young, Wang, Shifeng, Senechal, Patti, Sun, Wei, Roland, Kenneth L., Curtiss, Roy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887840/
https://ncbi.nlm.nih.gov/pubmed/20585446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011142
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