Live Recombinant Salmonella Typhi Vaccines Constructed to Investigate the Role of rpoS in Eliciting Immunity to a Heterologous Antigen

We hypothesized that the immunogenicity of live Salmonella enterica serovar Typhi vaccines expressing heterologous antigens depends, at least in part, on its rpoS status. As part of our project to develop a recombinant attenuated S. Typhi vaccine (RASTyV) to prevent pneumococcal diseases in infants...

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Main Authors: Shi, Huoying, Santander, Javier, Brenneman, Karen E., Wanda, Soo-Young, Wang, Shifeng, Senechal, Patti, Sun, Wei, Roland, Kenneth L., Curtiss, Roy
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887840/
https://ncbi.nlm.nih.gov/pubmed/20585446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011142
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