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Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase specific TCR transgenic mice

Generalized vitiligo is thought to have an autoimmune etiology, and has been correlated with the presence of CD8 T cells specific for melanocyte differentiation antigen. However, limited animal models for the disease have hampered its understanding. Thus, we generated TCR transgenic mice that recogn...

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書誌詳細
主要な著者: Gregg, Randal K., Nichols, Lisa, Chen, Yiming, Lu, Bao, Engelhard, Victor H.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887735/
https://ncbi.nlm.nih.gov/pubmed/20083666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902778
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