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Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase specific TCR transgenic mice

Generalized vitiligo is thought to have an autoimmune etiology, and has been correlated with the presence of CD8 T cells specific for melanocyte differentiation antigen. However, limited animal models for the disease have hampered its understanding. Thus, we generated TCR transgenic mice that recogn...

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Autors principals: Gregg, Randal K., Nichols, Lisa, Chen, Yiming, Lu, Bao, Engelhard, Victor H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887735/
https://ncbi.nlm.nih.gov/pubmed/20083666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902778
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