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Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast Cancer

PURPOSE: We studied the expression levels of cyclins B1, D1, and E1 and the implications of cyclin overexpression for patient outcomes in distinct breast cancer subtypes defined by clinical variables and transcriptional profiling. EXPERIMENTAL DESIGN: The expression levels of cyclins B1, D1, and E1...

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Detalhes bibliográficos
Main Authors: Agarwal, Roshan, Gonzalez-Angulo, Ana-Maria, Myhre, Simen, Carey, Mark, Lee, Ju-Seog, Overgaard, Jens, Alsner, Jan, Stemke-Hale, Katherine, Lluch, Ana, Neve, Richard M., Kuo, Wen Lin, Sorlie, Therese, Sahin, Aysegul, Valero, Vicente, Keyomarsi, Khandan, Gray, Joe W., Borresen-Dale, Anne-Lise, Mills, Gordon B., Hennessy, Bryan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887710/
https://ncbi.nlm.nih.gov/pubmed/19470724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3293
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