Silencing Nox4 in the Paraventricular Nucleus Improves Myocardial Infarction-Induced Cardiac Dysfunction by Attenuating Sympathoexcitation and Peri-infarct Apoptosis

RATIONALE: Myocardial infarction (MI)-induced heart failure (HF) is characterized by central nervous system (CNS)-driven sympathoexcitation and deteriorating cardiac function. The paraventricular nucleus (PVN) of the hypothalamus is a key regulator of sympathetic nerve activity and is implicated in...

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Detalhes bibliográficos
Main Authors: Infanger, David W., Cao, Xian, Butler, Scott D., Burmeister, Melissa A., Zhou, Yi, Stupinski, John A., Sharma, Ram V., Davisson, Robin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887701/
https://ncbi.nlm.nih.gov/pubmed/20413786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213025
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