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Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin-II

The renin angiotensin system (RAS) exerts a tremendous influence over fluid balance and arterial pressure. Angiotensin II (Ang-II), the effector peptide of the RAS, acts in the CNS to regulate neurohumoral outflow and thirst. Dysregulation of Ang-II signaling in the CNS is implicated in cardiovascul...

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Detalhes bibliográficos
Main Authors: Peterson, Jeffrey R., Burmeister, Melissa A., Tian, Xin, Zhou, Yi, Guruju, Mallikarjuna R., Stupinski, John A., Sharma, Ram V., Davisson, Robin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773438/
https://ncbi.nlm.nih.gov/pubmed/19805637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.140087
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