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Mutation of Archaeal Isopentenyl Phosphate Kinase Highlights Mechanism and Guides Phosphorylation of Additional Isoprenoid Monophosphates

[Image: see text] The biosynthesis of isopentenyl diphosphate (IPP) from either the mevalonate (MVA) or the 1-deoxy-d-xylulose 5-phosphate (DXP) pathway provides the key metabolite for primary and secondary isoprenoid biosynthesis. Isoprenoid metabolism plays crucial roles in membrane stability, ste...

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Detalhes bibliográficos
Main Authors: Dellas, Nikki, Noel, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887675/
https://ncbi.nlm.nih.gov/pubmed/20392112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb1000313
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