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Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

The idea of “date” and “party” hubs has been influential in the study of protein–protein interaction networks. Date hubs display low co-expression with their partners, whilst party hubs have high co-expression. It was proposed that party hubs are local coordinators whereas date hubs are global conne...

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Detalhes bibliográficos
Main Authors: Agarwal, Sumeet, Deane, Charlotte M., Porter, Mason A., Jones, Nick S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887459/
https://ncbi.nlm.nih.gov/pubmed/20585543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000817
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