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Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

The idea of “date” and “party” hubs has been influential in the study of protein–protein interaction networks. Date hubs display low co-expression with their partners, whilst party hubs have high co-expression. It was proposed that party hubs are local coordinators whereas date hubs are global conne...

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Détails bibliographiques
Auteurs principaux: Agarwal, Sumeet, Deane, Charlotte M., Porter, Mason A., Jones, Nick S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887459/
https://ncbi.nlm.nih.gov/pubmed/20585543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000817
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