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Blockade of TRPM7 Channel Activity and Cell Death by Inhibitors of 5-Lipoxygenase

TRPM7 is a ubiquitous divalent-selective ion channel with its own kinase domain. Recent studies have shown that suppression of TRPM7 protein expression by RNA interference increases resistance to ischemia-induced neuronal cell death in vivo and in vitro, making the channel a potentially attractive p...

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Detalhes bibliográficos
Main Authors: Chen, Hsiang-Chin, Xie, Jia, Zhang, Zheng, Su, Li-Ting, Yue, Lixia, Runnels, Loren W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887440/
https://ncbi.nlm.nih.gov/pubmed/20567598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011161
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