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TRPM7 Activates m-Calpain by Stress-Dependent Stimulation of p38 MAPK and c-Jun N-Terminal Kinase
TRPM7 is a Ca(2+) and Mg(2+) permeant ion channel in possession of its own kinase domain. In a previous study we showed that overexpression of the channel-kinase in HEK-293 cells produced cell rounding and loss of adhesion which was dependent upon the Ca(2+)-dependent protease m-calpain. The TRPM7-e...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825087/ https://ncbi.nlm.nih.gov/pubmed/20070945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.014 |
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