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Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues

Imprinted genes in mice and humans mainly occur in clusters that are associated with differential DNA methylation of an imprint control element (ICE) and at least one nonprotein-coding RNA (ncRNA). Imprinted gene silencing is achieved by parental-specific insulator activity of the unmethylated ICE m...

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Bibliografiske detaljer
Main Authors: Hudson, QJ, Kulinski, TM, Huetter, SP, Barlow, DP
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887385/
https://ncbi.nlm.nih.gov/pubmed/20234385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2010.23
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