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Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues

Imprinted genes in mice and humans mainly occur in clusters that are associated with differential DNA methylation of an imprint control element (ICE) and at least one nonprotein-coding RNA (ncRNA). Imprinted gene silencing is achieved by parental-specific insulator activity of the unmethylated ICE m...

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Bibliographic Details
Main Authors: Hudson, QJ, Kulinski, TM, Huetter, SP, Barlow, DP
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887385/
https://ncbi.nlm.nih.gov/pubmed/20234385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2010.23
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