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Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
The endoplasmic reticulum (ER) is the major site in the cell for protein folding and trafficking and is central to many cellular functions. Failure of the ER's adaptive capacity results in activation of the unfolded protein response (UPR), which intersects with many different inflammatory and s...
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| Natura: | Artigo |
| Lingua: | Inglês |
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2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887297/ https://ncbi.nlm.nih.gov/pubmed/20303879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.034 |
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