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Metalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells

Inflammation is often accompanied by robust angiogenesis. Vascular endothelial cells (ECs) express erbB receptors and their ligand, neuregulin-1, and can respond to neuregulin by proliferation and angiogenesis. We hypothesized that some growth factor-like responses of ECs to inflammatory cytokines c...

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Bibliographische Detailangaben
Hauptverfasser: Kalinowski, April, Plowes, Nicola J. R., Huang, Qunhua, Berdejo-Izquierdo, Carla, Russell, Raymond R., Russell, Kerry S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887255/
https://ncbi.nlm.nih.gov/pubmed/20215529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-129072
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